中国科学院北京基因组研究所成立于2003年11月28日。2007年10月，研究所迁至临时所址，2013年1月，迁至中国科学院奥运村科技园区内的永久所址。
中国科学院北京基因组研究所发展定位为：面向中国人口健康和社会可持续发展的重大战略需求与生命科学前沿，重点研究基因组结构、变异、功能及其演化规律，加强基因组学与其他学科的交叉融合，发展基因组学的新理论、新方法和新技术，成为基因组学原始创新研究基地、创新人才培养基地和卓越科学中心，为保障人类社会的健康发展做出重大贡献。
基因组所现有“中国科学院基因组科学与信息重点实验室”，“中国科学院精准基因组医学重点实验室”及“国家基因组科学数据中心”三个科研体系及“基因组技术创新中心”、“学报编辑部”两个支撑体系；1个生物学博士后流动站。配备了从一代到三代所有测序机型；建立了完善的试验与测序技术体系和流程；具备一天产出100G的测序能力；拥有大片段文库构建，微量DNA和RNA样品建库、测序，RNA甲基化测序，多种测序技术组合使用，解决复杂基因组测序难点。
Beijing Institute of Genomics, Chinese Academy of Sciences was founded on November 28, 2003. In October 2007, the Institute moved to a temporary location, and in January 2013, it moved to a permanent location within the Science and Technology Park of the Olympic Village of the Chinese Academy of Sciences.
Beijing Institute of Genomics, Chinese Academy of Sciences To meet the major strategic needs of China's population health and social sustainable development and the frontier of life science, it focuses on the study of genome structure, variation, function and its evolution law, strengthens the cross-integration of genomics and other disciplines, develops new theories, new methods and new technologies in genomics, and becomes the original innovation research base, innovative talent training base and scientific center of excellence in genomics. It has made significant contributions to the healthy development of human society.
The Institute of Genomics has three scientific research systems: Key Laboratory of Genome Science and Information, Chinese Academy of Sciences; Key Laboratory of Precision Genome Medicine, Chinese Academy of Sciences; National Data Center for Genome Sciences; and two supporting systems: Genome Technology Innovation Center and Journal Editorial Department. 1 Biology postdoctoral mobile station. Equipped with all sequencing machines from generation 1 to generation 3; Established a perfect test and sequencing technology system and process; Sequencing capacity of 100G per day; It has large fragment library construction, trace DNA and RNA sample library construction, sequencing, RNA methylation sequencing, and the combination of multiple sequencing technologies to solve the difficulties of complex genome sequencing.