美国国立普通医学科学研究所（NIGMS）是美国国立卫生研究院（NIH）的27个机构或中心之一。NIGMS的预算为30亿美元，为5，500多名研究人员和5，000项研究补助金提供支持。该研究所在资助继续获得诺贝尔奖的科学家方面有着良好的记录，其中包括50名化学奖和44名生理学或医学奖。
NIGMS资助的科学家研究了生命系统如何在从分子和细胞到组织，整个生物体和种群的一系列水平上的工作。该研究所还支持某些临床领域的研究，主要是那些影响多个器官系统的领域。为了确保研究企业的活力和持续的生产力，NIGMS在培训下一代科学家，加强科学劳动力的多样性以及在全国范围内发展研究能力方面发挥了领导作用。
所有NIH研究所和中心都支持与其任务区域内的疾病，器官系统，生命阶段或人群相关的基础研究。相比之下，NIGMS支持不关注这些特定领域的基础研究。其研究任务旨在了解生物体背后的原理，机制和过程，通常使用研究模型。NIGMS还支持开发基本方法和新技术来实现其使命。支持的研究可以利用特定的细胞或器官系统，如果它们作为理解一般原理的模型。在大多数情况下，以获取有关特定器官或器官系统或特定疾病或病症的病理生理学，治疗或治愈的知识的总体目标的研究将更适合另一个研究所或中心。
该研究所分为以下部门，支持一系列科学领域的研究，研究培训和能力建设：
生物物理学、生物医学技术和计算生物科学系；
遗传学和分子生物学、细胞生物学和发育生物学系；
药理生理学和生物化学系；
研究能力建设司；
培训、劳动力发展和多样性司 。
The National Institute of General Medical Sciences (NIGMS) is one of 27 institutions or centers of the National Institutes of Health (NIH). With a budget of $3 billion, NIGMS supports more than 5,500 researchers and 5,000 research grants. The institute has a proven track record of funding scientists who go on to win Nobel Prizes, including 50 prizes in chemistry and 44 prizes in physiology or medicine.
NIGMS funded scientists have studied how living systems work at a range of levels, from molecules and cells to tissues, organisms and populations as a whole. The institute also supports research in certain clinical areas, primarily those that affect multiple organ systems. To ensure the vitality and continued productivity of research enterprises, NIGMS has played a leading role in training the next generation of scientists, enhancing the diversity of the scientific workforce, and developing research capacity across the country.
All NIH institutes and centers support basic research related to disease, organ system, life stage or population within their mission area. In contrast, NIGMS supports basic research that does not focus on these specific areas. Its research missions are aimed at understanding the principles, mechanisms and processes behind living organisms, often using research models. NIGMS also supports the development of basic methods and new technologies to achieve its mission. Supported research can utilize specific cellular or organ systems if they serve as models for understanding general principles. In most cases, the study of the overall goal of obtaining knowledge about the pathophysiology, treatment or cure of a particular organ or organ system or specific disease or condition would be more suitable for another institute or center.
The Institute is divided into the following sectors that support research, research training and capacity building in a range of scientific fields:
Department of Biophysics, Biomedical Technology and Computational Biosciences;
Department of Genetics and Molecular Biology, Cell Biology and Developmental Biology;
Department of Pharmacophysiology and Biochemistry;
Research Capacity-Building Division;
Training, Workforce Development and Diversity Division.