创新背景

农药破坏线粒体功能，并破坏ATP的生产，ATP是驱动细胞功能的能量供应源。这导致暴露于新烟碱类物质的蜜蜂的机动性降低，导致它们饿死，无法养活自己。

创新过程

研究人员使用了来自商业蜂箱的四组蜜蜂，每个蜂群中有400多只蜜蜂。两组暴露于新烟碱类药物吡虫啉10天，其中一组也在同一时间接受光疗-15分钟的近红外光（670nm）照射到蜂箱中，每天两次。

中毒但未接受光疗的蜜蜂的活动性迅速下降，其ATP水平也迅速下降，存活率也相应下降。被毒害但也接受了光疗的蜜蜂具有明显更好的活动性和存活率，寿命和功能与未被毒害的蜜蜂一样长。其中一组在未中毒的情况下接受光疗，其生存率甚至高于对照组。研究人员发现，深红光不会干扰蜜蜂的行为，因为它们看不见。

其他研究表明，长波长光处理可以减少衰老过程导致的线粒体退化。即使对不受杀虫剂影响的蜜蜂也有好处，因此，如果蜂群暴露于新烟碱类物质，光疗可以成为防止生命损失的有效手段。

虽然光疗作为预防措施效果最好，但研究人员发现，只要在接触农药后几天内开始治疗，它也可以作为对农药接触事件的治疗。

UCL眼科的研究人员一直在研究近红外光疗法，因为它不仅对蜜蜂有好处，对包括人类在内的其他动物也有好处，特别是可以对抗衰老和一系列神经疾病的影响。

创新价值

通过向受有毒农药影响的蜜蜂照射深红光，它们可以恢复，因为它改善了线粒体和视觉功能，使它们能够四处走动并再次进食。

创新关键点

当一个神经细胞比其他细胞消耗更多的能量，或者因为缺乏能量而受到挑战时，红光疗法可以通过改善线粒体功能来促进它。本质上，它为细胞的电池充电。

Using phototherapy to save bees from lethal pesticides

The researchers used four groups of bees from commercial hives, each containing more than 400 bees. Two groups were exposed to the neonicotinic drug imidacloprid for 10 days, and one group also received phototherapy at the same time - 15 minutes of near-infrared light (670nm) was irradiated into the hive twice a day.
The activity of bees poisoned but not treated with phototherapy decreased rapidly, the ATP level of bees also decreased rapidly, and the survival rate decreased accordingly. The bees that were poisoned but also received phototherapy had significantly better activity and survival rate, and the life span and function were as long as the bees that were not poisoned. One group received phototherapy without poisoning, and its survival rate was even higher than that of the control group. The researchers found that deep red light did not interfere with the behavior of bees because they could not see.
Other studies have shown that long wavelength light treatment can reduce mitochondrial degradation caused by aging process. Even for bees that are not affected by pesticides, phototherapy can be an effective means to prevent loss of life if bees are exposed to neonicotine.
Although phototherapy has the best effect as a preventive measure, the researchers found that as long as the treatment is started within a few days after exposure to pesticides, it can also be used as a treatment for pesticide exposure events.
UCL ophthalmologists have been studying near-infrared light therapy because it is not only beneficial to bees, but also to other animals including humans, especially to fight the effects of aging and a series of neurological diseases.